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目的对比宫颈环形电切术(LEEP)与冷刀锥切术(CKC)两种术式对宫颈上皮内瘤变(CIN)的治疗效果。方法随机选取2011年12月—2013年9月商丘市妇幼保健院收治的128例CINⅢ患者,随机分为观察组和对照组各64例,观察组应用宫颈环形电切术治疗,对照组应用冷刀锥切术治疗。对两组手术时间、手术出血量、切口愈合时间和治疗效果等方面进行比较。结果观察组在手术时间、手术出血量、切口愈合时间等方面明显优于对照组,差异有统计学意义(P<0.05)。观察组愈合率、病灶残余率、复发率及患者满意率分别为90.61%、4.69%、4.69%、92.19%,均优于对照组(P<0.05)。结论 LEEP较之CKC治疗宫颈上皮内瘤变更加安全有效,且手术时间短、出血量少,更适用于基层医院。
Objective To compare the therapeutic effect of cervical ring electrosurgery (LEEP) and cold knife conization (CKC) on cervical intraepithelial neoplasia (CIN). Methods A total of 128 patients with CIN Ⅲ who were treated in Shangqiu MCH hospital from December 2011 to September 2013 were randomly divided into observation group and control group with 64 cases each. The observation group was treated with cervical ring excision, while the control group was treated with cold Cone knife surgery. The two groups of operation time, surgical bleeding, incision healing time and treatment and other aspects were compared. Results The observation group was significantly better than the control group in terms of operation time, blood loss and incision healing time, the difference was statistically significant (P <0.05). The healing rate, lesion residual rate, recurrence rate and patient satisfaction in the observation group were 90.61%, 4.69%, 4.69% and 92.19%, respectively, which were better than those in the control group (P <0.05). Conclusions LEEP is more safe and effective than CKC in the treatment of cervical intraepithelial neoplasia, and the operation time is short, less bleeding, more suitable for primary hospital.