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骨性关节炎(OA)是一种常见的骨骼系统疾病,以滑膜关节中进展性软骨丢失为特征,常引起关节的疼痛及活动受限。高血压是一种以动脉血压持续升高为主要表现的心血管系统疾病,两者虽是不同系统的疾病,却在中老年人群中时常共存。现对这两种疾病的流行病学、与代谢综合征的关系、与雌激素受体基因多态性的关系、药物及失眠对OA患者血压的影响四个方面进行综述,以探讨OA和高血压之间可能存在的内在相关性。
Osteoarthritis (OA) is a common skeletal system disorder characterized by progressive loss of cartilage in synovial joints, often causing pain and limited mobility in the joints. Hypertension is a type of cardiovascular disease characterized by the continuous increase of arterial blood pressure. Although both are diseases of different systems, they often coexist in the middle-aged and elderly people. Now the epidemiology of these two diseases, and metabolic syndrome, estrogen receptor gene polymorphisms and the relationship between drugs and insomnia on the impact of blood pressure in patients with OA in four areas to explore the OA and high Possible correlation between blood pressure.