一、泻下剂的涵义是什么?因何立法? 答泻下剂是指凡以泻下药物为主组成,具有攻逐里实等作用,用来治疗里实证的方剂。所谓攻逐里实:主要是通过泻下大便,以排除胃肠内的积滞(如宿食、燥屎等),荡涤实热,攻逐体内积水等等。临床常用于治疗里实证。里实证包括范围很广,本类方剂仅适用于寒热积滞,水饮内停一类病证。泻下剂是根据《素问·阴阳应象大论》:“其下者,引而竭之;中满者,泻之于内;……其实者,散而泻之”及《素问·至真要大论》:“留者攻之”的原则而立法的。属于“八法”中的“下法”。二、泻下剂有何临床意义?应用时需注意哪些问题? What is the meaning of a purgative agent? What legislation does it mean? Answering purgative agents refers to those formulas that use purgative drugs as the main component and have the role of attack and actual use in treatment. The so-called attack in the real: mainly through the purgatory stool, in order to rule out the accumulation of gastrointestinal stagnation (such as food, dry pimple, etc.), wash away real heat, attack the body of stagnant water and so on. Clinically used for treatment in the empirical. The empirical evidence includes a wide range of prescriptions. This type of prescription is only applicable to cold and heat stagnation, and the type of illness is stopped in drinking water. The purgative agent is based on the “Principles of Yin-Yang and Ying-Yang should be like”: “The next one is, and then the exhaustion is; the one is full, the one is diarrhea; the other is, in fact, is scattered and diarrhea.” It is really necessary to talk about the principle of “the offender attacking” and legislate. It belongs to the “Failure Law” in the “Eight Laws”. Second, the clinical significance of the purgative agent? What issues should be paid attention to when applying?