中耳癌(carcinoma of the middle ear)少见,占全身恶性肿瘤的0.3%,多为单侧,Suzuki等曾报道6例双侧中耳鳞状细胞癌;男性多见于女性,年龄多为40～60岁。中耳癌发病隐匿,早期常被忽视,待症状明显时,多已属晚期,常侵犯岩骨、颅内等处。复习文献,有利于进一步认识中耳癌的诊治。 1 病因目前中耳癌病因仍不十分清楚,慢性中耳炎可能是其诱因之一,文献报道70%～90%中耳癌有慢性中耳炎史或有放射治疗史,正常鼓室粘膜上皮在慢性炎症的长期刺激下,有可能化生演变成复层鳞状上皮,存在恶变的可 Carcinoma of the middle ear rare, accounting for 0.3% of systemic malignant tumors, mostly unilateral, Suzuki et al reported 6 cases of bilateral middle ear squamous cell carcinoma; men more common in women, aged more than 40 ~ 60 years old. Middle ear cancer occult onset, often overlooked early, when the symptoms are obvious, many are late, often invading rock, intracranial and other places. Review of the literature is conducive to further understanding of the diagnosis and treatment of middle ear cancer. 1 etiology of the cause of the disease is still not very clear middle ear, chronic otitis media may be one of its incentives reported in the literature 70% to 90% of the middle ear cancer has a history of chronic otitis media or a history of radiation therapy, normal tympanum mucosal epithelium in long-term chronic inflammation Stimulation, it is possible that metaplasia evolved into stratified squamous epithelium, there may be malignant transformation