葛根素(puerarinum)为山东省医科院药物研究所从豆科植物野葛根中提取的一种异黄酮类化合物精制成葛根素注射液,是一种β受体拮抗剂.为确保临床应用的安全,进行了药物的短期致突及致畸试验,其结果如下: Ames试验 采用TA97,TA98,TA100,TA102为测试菌株,选取1,5,50,500,5000μg/皿,并设空白,溶剂及阳性对照.结果表明:各实验组与阴性对照组,在加S9和不加S9的实验中,其回变菌落数基本相 Puerarin (puerarinum) is a kind of β-receptor antagonist, an isoflavone extracted from Pueraria lobata of Shandong Medical Institute Institute of Materia Medica, is a β-receptor antagonist. To ensure the clinical application The results were as follows: Ames test using TA97, TA98, TA100, TA102 as test strains, select 1, 5, 50, 500, 5000μg / dish, and set the blank, solvent and positive The results showed that in each experimental group and negative control group, in the experiment of adding S9 and not adding S9, the number of returned colonies was basically