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目的探讨奥曲肽联合奥美拉唑治疗非静脉曲张性消化道出血的临床疗效。方法选取灵寿县医院2015—2016年收治的非静脉曲张性上消化道出血患者106例,根据随机数字表法分为对照组和观察组,各53例。患者入院后均采用常规基础治疗,对照组患者采用奥美拉唑治疗,观察组患者在对照组基础上给予奥曲肽治疗,两组患者均持续治疗3 d。比较两组患者的临床疗效、止血时间、输血量、再出血率及血红蛋白水平。结果观察组患者治疗总有效率高于对照组(P<0.05)。观察组患者止血时间短于对照组,输血量少于对照组,再出血率、血红蛋白水平低于对照组(P<0.05)。结论采用奥曲肽联合奥美拉唑治疗非静脉曲张性消化道出血的临床疗效确切,止血效果明显,且安全可靠。
Objective To investigate the clinical efficacy of octreotide combined with omeprazole in the treatment of non-variceal hemorrhage. Methods 106 cases of non-variceal upper gastrointestinal bleeding admitted to Lingshou County Hospital from 2015 to 2016 were divided into control group and observation group according to random number table method, with 53 cases in each group. Patients were admitted to the hospital after treatment with conventional basic treatment, patients in the control group were treated with omeprazole, patients in the observation group were given octreotide on the basis of the control group, and both groups were treated for 3 days. The clinical efficacy, bleeding time, blood transfusion, rebleeding rate and hemoglobin level were compared between the two groups. Results The total effective rate of observation group was higher than that of control group (P <0.05). The bleeding time in the observation group was shorter than that in the control group, the blood transfusion volume was less than the control group, the rebleeding rate and the hemoglobin level were lower than those in the control group (P <0.05). Conclusion The clinical efficacy of octreotide combined with omeprazole in the treatment of non-variceal hemorrhage is obvious, and the hemostatic effect is obvious and safe.