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０引言我们和其他作者先前的研究表明，在正常人血清中存在着抗角蛋白自身抗体．目前尚不清楚该抗体群的功能作用．但已有实验提示，血清抗角蛋白抗体量或质的变化与某些病变相关．体外实验证明，纯化的抗角蛋白自身抗体可以影响皮肤角航细胞的代谢活动和生长特性．为了深入开
0 Introduction We and other authors previous studies have shown that anti-keratin autoantibodies exist in normal human serum. It is not yet clear what the functional role of this antibody population is. However, some experiments suggest that serum anti-keratin antibody quantity or quality changes associated with some lesions. In vitro experiments show that the purified anti-keratin autoantibodies can affect the metabolic activity and growth characteristics of keratinocytes in the skin. In order to go further