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目的探讨中医辨证论治配合化疗对多发性骨髓瘤肾病患者生存质量的影响及应用价值。方法选取2013年4月—2015年4月收治的60例多发性骨髓瘤肾病患者作为研究对象,随机分为对照组和实验组各30例。对照组给予常规化疗,实验组在对照组的基础上联合中医辨证论治治疗。对比两组患者的生存质量及不良反应发生情况。计数资料采用χ2检验,P<0.05为差异有统计学意义。结果实验组生存质量总改善率为96.7%,显著高于对照组的73.3%,差异有统计学意义(P<0.05)。实验组不良反应发生率为20.0%,显著低于对照组的56.7%,差异有统计学意义(P<0.05)。结论对多发性骨髓瘤肾病患者应用中医辨证论治配合化疗可改善患者生存质量,且安全可靠,值得临床进一步推广应用。
Objective To investigate the effect of syndrome differentiation of traditional Chinese medicine (TCM) and chemotherapy on quality of life in patients with multiple myeloma and its clinical value. Methods Sixty patients with multiple myeloma and nephropathy admitted from April 2013 to April 2015 were selected as study subjects and randomly divided into control group and experimental group with 30 cases each. Control group given conventional chemotherapy, experimental group in the control group based on the combination of TCM diagnosis and treatment. The quality of life and adverse reactions of two groups were compared. Count data using χ2 test, P <0.05 for the difference was statistically significant. Results The total improvement rate of quality of life in experimental group was 96.7%, which was significantly higher than that in control group (73.3%), the difference was statistically significant (P <0.05). The incidence of adverse reactions in the experimental group was 20.0%, which was significantly lower than that in the control group (56.7%), the difference was statistically significant (P <0.05). Conclusion Multiple myeloma patients with nephropathy syndrome differentiation treatment with traditional Chinese medicine can improve the quality of life in patients with quality of life, and safe and reliable, it is worth further clinical application.