不同程度的瘙痒是真性红细胞增多症(PV)患者的一个常见但具有特征性的症状。某些PV患者尽管红细胞容量已减少,其瘙痒难以常用的抗痒方法治疗。作者报道6例这样的PV患者,经单独口服铁剂后瘙痒完全消失,提示严重的缺铁可引起某些PV患者的瘙痒症状。 6例患者,男2女4,年龄58～76岁,符合PV的诊断标准,均有程度不同的肝脾肿大。就诊时:血红蛋白(Hb)18.2g(范围17.1～19.5),白细胞计数19.0×10~9/l(范围12.5～26)、血小板485×10~9/l(范 Different degrees of pruritus are a common but characteristic symptom in patients with polycythemia vera (PV). In some patients with PV, the volume of erythrocytes has decreased, and itching is often difficult to treat with anti-itch. The authors report that in six PV patients such as this, the complete absence of pruritus after oral administration of iron alone suggested that severe iron deficiency may cause pruritus in some PV patients. 6 patients, 2 males and 4 females, aged 58 to 76 years, in line with the diagnostic criteria of PV, have varying degrees of hepatosplenomegaly. At the time of diagnosis, hemoglobin (Hb) 18.2g (range 17.1-19.5), white blood cell count 19.0 × 10-9 / l (range 12.5-26), platelets 485 × 10-9 / l