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测定209例肾透析患者血液中HBV-DNA和HCV-RNA,阳性率HBV-DNA为2.4%、HCV-RNA为16.3%;76例肾移植后患者阳性率HBV-DNA为2.6%、HCV-RNA为23.7%;对照组阳性率HBV-DNA为1.8%、HCV-RNA为2.0%。HBV-DNA阳性率在各组间无显著差异,P>0.05;血液透析组和肾移植组HCV-RNA阳性率高于对照组,且有显著性差异P<0.01;肾移植组高于肾透析组,但无显著性差异,P>0.05。HBV-DNA阳性合并HCV-RNA阳性为42.9%(3/7)。52例HCV-RNA阳性患者基因分型为Ⅱ型76.9%、ⅡⅢ型11.5%、Ⅲ型11.5%。介于目前的状况,对献血检测,对阳性患者进行HBV-DNA、HCV-RNA检测,对阳性患者实行分机透析,是降低血透及肾移植患者乙、丙型肝炎病毒医院感染的关键。
HBV-DNA and HCV-RNA in 209 renal dialysis patients were determined. The positive rate of HBV-DNA was 2.4% and HCV-RNA was 16.3%. The positive rate of HBV-DNA in 76 patients after renal transplantation was 2. 6%, HCV-RNA was 23.7%; The positive rate of HBV-DNA in control group was 1.8% and that of HCV-RNA was 2.0%. The positive rate of HBV-DNA in each group had no significant difference (P> 0.05). The positive rate of HCV-RNA in hemodialysis group and renal transplantation group was higher than that in control group, and there was a significant difference P <0.01; Higher than renal dialysis group, but no significant difference, P> 0.05. Positive HBV-DNA combined with HCV-RNA was 42.9% (3/7). Genotypes of 52 HCV-RNA positive patients were type II 76.9%, type II III 11.5% and type III 11.5%. In the current situation, blood donation testing, positive HBV-DNA and HCV-RNA testing in positive patients and extension dialysis in positive patients are the key to reducing hospital infection of Hepatitis B and Hepatitis C virus in hemodialysis patients and renal transplant recipients.