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肥胖是日益增多的营养性疾病,身体脂肪过量,常伴胰岛素抵抗,两者均为心血管病危险因素,同时存在会增加心血管疾病的发病。新疆是一个多民族严寒地区,维吾尔族人主要以肉食为主,因此肥胖及冠心病的发病率很高。瘦素主要是脂肪细胞分泌的多肽类激素。由于瘦素与冠心病的危险因素如 BMI、肥胖、IR、高胰岛素血症、高甘油三脂、高血压等有正相关关系,故有学者认为瘦素水平升高使冠心病危险增加,但国内外有些研究得出相反的结论。本研究以新疆维吾尔族人群为对象,探讨瘦素与冠心病患者危险因素的相关性,为提高少数民族地区心血管疾病的防治水平提供新的策略。
Obesity is a growing number of nutritional diseases, excessive body fat, often accompanied by insulin resistance, both cardiovascular risk factors, while the presence of cardiovascular disease will increase the incidence. Xinjiang is a multi-ethnic area with severe cold. Uighur people mainly depend on meat. Therefore, the incidence of obesity and coronary heart disease is very high. Leptin is mainly secreted by fat cells peptide hormone. As leptin and coronary heart disease risk factors such as BMI, obesity, IR, hyperinsulinemia, hypertriglyceridemia, hypertension and so has a positive correlation, so some scholars believe that increased leptin levels of coronary heart disease risk increase, but Some studies at home and abroad come to the opposite conclusion. In this study, we investigated the relationship between leptin and risk factors of coronary heart disease in Xinjiang Uygur population, and provided a new strategy to improve the prevention and treatment of cardiovascular disease in ethnic minority areas.