众所周知,甲醇的羰基化是液相中的钴、铑、镍、或铱金属络合物催化的。该反应也可由沸石或载有上述金属的活性炭催化剂进行气相催化。反应的主要产物是乙酸甲酯和醋酸。作者们已经报道,载于活性炭上的镍,在温和的条件(250℃,1.1MPa)下,对甲醇的气相羰基化表现了卓越的活性。 It is well known that the carbonylation of methanol is catalyzed by cobalt, rhodium, nickel, or iridium metal complexes in the liquid phase. The reaction can also be gas phase catalyzed by zeolites or activated carbon catalysts carrying the above metals. The main products of the reaction are methyl acetate and acetic acid. The authors have reported that nickel supported on activated carbon showed excellent activity for gas phase carbonylation of methanol under mild conditions (250 ° C, 1.1 MPa).