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目的:探讨乳腺增生症与子宫不同术式术后相关性。方法:对384例因子宫良性病变行子宫不同术式治疗的患者,进行术前、术后3个月、6个月及1年血激素FSH、LH、PRL、E2、P检测,并与发生乳腺增生症及相关症状进行对比。结果:全子宫切除组、次全子宫切除组术后3个月、6个月及1年FSH、LH、PRL明显升高,E2明显下降,与术前、肌瘤剔除组及对照组比较差异有显著性(P<0.05);全子宫切除组、次全子宫切除组术后发生乳腺增生及各种症状与肌瘤剔除组和对照组比较差异有显著性(P<0.05)。结论:子宫切除术后体内激素水平发生改变,从而导致乳腺增生,并出现一系列相关症状;子宫肌瘤剔除术后因体内激素水平无明显变化,故发生乳腺增生几率小。
Objective: To investigate the correlation between breast hyperplasia and different operation of uterus. Methods: 384 patients with uterine benign lesions were treated with different operation of the uterus. Preoperative, postoperative 3 months, 6 months and 1 year of serum FSH, LH, PRL, E2, P were detected, and with the occurrence Hyperplasia of mammary glands and related symptoms were compared. Results: The FSH, LH and PRL at 3 months, 6 months and 1 year after hysterectomy and subtotal hysterectomy were significantly increased, E2 significantly decreased, compared with preoperative myomectomy group and control group (P <0.05). There was a significant difference between the hysterectomy group and the subtotal hysterectomy group in the occurrence of breast hyperplasia and various symptoms compared with the myomectomy group and the control group (P <0.05). Conclusions: Hormone levels in the body after hysterectomy change, resulting in hyperplasia of mammary glands, and a series of related symptoms. After hysterectomy, there is no obvious change of hormone level in the body, so the risk of mammary gland hyperplasia is low.