作者回顾4年来波斯顿一医疗中心外科病旁中严重念珠菌感染的诊断与治疗经验。方法复习从血液、胆汁、脑脊液、胸水、腹水、心包液、软组织(不包括皮肤及粘膜)、外科脓肿及深部创口抽吸物中分离出念珠菌的所有外科患者的临床记录,仅包括临床上有创口感染,且从创口中分离出大量念珠菌或分离出的念珠菌为唯一细菌者。复习同期外科患者的尸检记录,包括有深部念珠菌感染证据者,但不包括 The authors review the experience of diagnosis and treatment of severe Candida infections in the surgical area at Boston Medical Center over a four-year period. Methods The clinical records of all surgical patients who had Candida isolated from blood, bile, cerebrospinal fluid, pleural effusion, ascites, pericardial fluid, soft tissue (excluding skin and mucosa), surgical abscesses and deep wound aspirates were reviewed and included clinically A wound infection, and isolated from the wound a large number of candida or Candida isolated as the only bacteria. Review of autopsy records for surgical patients of the same period, including evidence of deep candidiasis but excluding