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目的探讨骨质疏松(OP)对患者生活质量(QOL)的影响,尤其是对未骨折OP患者。方法97例绝经后患者(年龄50～81岁),其中60例OP患者,37例OP+骨折患者。采用国际流行的OP生活量表(QUALEFFO-41评分法)调查QOL和Zung抑郁自评量表观察抑郁评分。并选取30例年龄匹配的女性甲状腺功能减退患者为对照组。结果OP的家族史和脊柱的Tokuhashi修正评分在OP组和OP+骨折组均无显著差异。OP+骨折组Zung抑郁量表评分明显高于对照组(P<0.05)。OP组和OP+骨折组的疼痛、健康感知及总分与对照组比较有显著差异(P<0.01,P<0.05,P<0.001)。OP+骨折组的躯体功能及社会功能与OP组和对照组比较有显著差异(P<0.001,P<0.01)。结论OP患者的QOL应受到关注,以制订适宜的咨询、支持及护理干预措施来帮助患者掌握应对疾病的有效策略。
Objective To investigate the effect of osteoporosis (OP) on quality of life (QOL) in patients, especially for patients with no fracture OP. Methods A total of 97 postmenopausal patients (aged 50-81 years) including 60 OP and 37 OP + fractures were included in this study. The QOL and Zung depression self-rating scale were used to observe the depression score using the international popular OP-life scale (QUALEFFO-41 score method). 30 age-matched female hypothyroidism patients were selected as the control group. Results There was no significant difference in the family history of OP and the Tokuhashi revision of spine between the OP and OP + fracture groups. The scores of Zung depression scale in OP + fracture group were significantly higher than those in control group (P <0.05). The pain, health perception and total score in OP group and OP + fracture group were significantly different from those in control group (P <0.01, P <0.05, P <0.001). The body function and social function in OP + fracture group were significantly different from those in OP group and control group (P <0.001, P <0.01). Conclusion The QOL of patients with OP should receive attention to develop appropriate counseling, support and nursing interventions to help patients master the effective strategies for coping with the disease.