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百日咳是小儿呼吸道传染病,近年发现许多老药对其有较好疗效.兹介绍如下.1 人血清丙种球蛋白文献报道用本品治疗百日咳总有效率92.9%。机理是本品进入人体后与细菌毒素结合,起中和毒素、激活补体.促进吞噬细胞的吞噬作用,消灭病原体,加快呼吸道粘膜炎症的吸收。2 氯丙嗪(CPZ)有人用CPZ0.5～lmg·kg~(-1).1次.睡前顿服;强的松l～2mg·kg~(-1)·d~(-1).分3次口服;SMZ_(co)15～30mg·kg~(-1)·d~(-1),分2次口服,7d一疗程,治百日咳总有效率为63.5％。
Pertussis is a respiratory disease in children, found in recent years, many of the old drug has a good effect on it.It is described as follows.1 Human serum gamma globulin reported in the literature using this product pertussis total effective rate 92.9%. Mechanism is the product into the human body after combination with bacterial toxins, neutralizing toxins and activate complement, promote phagocytic phagocytosis, eliminate pathogens, and accelerate the absorption of respiratory mucosal inflammation. 2 CPZ was CPZ0.5 ~ lmg · kg ~ (-1) .1 times. Before going to bed clothes; prednisone l ~ 2mg · kg -1 (-1) d -1 . Oral administration was given orally three times; SMZ_ (co) was 15 ~ 30 mg · kg -1 · d -1, orally for 2 times and once a course of 7 days. The total effective rate of pertussis was 63.5%.