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血管内皮功能失调是动脉粥样硬化病理过程中的早期改变。血浆胆固醇水平升高是动脉粥样硬化重要的独立危险因素。动物实验以及临床试验均显示高胆固醇血症患者在动脉粥样硬化斑块形成之前即可出现血管内皮功能失调 ,主要表现为内皮依赖舒张功能障碍。许多大规模的临床试验发现?
Vascular endothelial dysfunction is an early change in the pathogenesis of atherosclerosis. Elevated plasma cholesterol is an important independent risk factor for atherosclerosis. Animal experiments and clinical trials have shown that patients with hypercholesterolemia vascular endothelial dysfunction before the formation of atherosclerotic plaques, mainly as endothelial dependent diastolic dysfunction. Many large-scale clinical trials found?