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为探讨脑络通胶囊抗鹌鹑动脉粥样硬化的机制，以食饵性高脂血症鹌鹑复制动脉粥样硬化模型，测量其血清中总胆固醇、甘油三脂，血浆中前列环素、血栓烷A2，脑组织中过氧化脂质、超氧化物歧化酶和谷胱甘肽过氧化物酶，并用评分法评估鹌鹑动粥样硬化的程度。结果发现，脑络通胶囊无降胆醇和甘油三酯的作用，但能显著升高超氧化物歧化酶的含量（P＜0．05），减轻动脉粥样硬化斑块的形成（P＜0．05）。提示，脑络通胶囊抑制动脉粥样硬化斑块形成的机理不是通过降血脂作用，而是通过抗氧化作用而奏效的。
In order to explore the mechanism of Naoluotong Capsule against atherosclerosis in the axillary artery, the atherosclerosis model was replicated with food-fat hyperlipidemia and its serum total cholesterol, triglyceride, plasma prostacyclin, and thromboxane A2 were measured. , Lipid peroxide, superoxide dismutase and glutathione peroxidase in brain tissue, and scores were used to assess the degree of atherosclerosis. The results showed that Naoluotong Capsule had no effect of reducing cholesterol and triglyceride, but could significantly increase the content of superoxide dismutase (P<0.05) and reduce the formation of atherosclerotic plaque (P<0. 05). It is suggested that the mechanism of Naoluotong Capsule in inhibiting the formation of atherosclerotic plaque is not through the effect of lowering blood lipids, but through the effect of antioxidation.