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目的分析前列腺结节超声造影(CEUS)的动态血管模式曲线(DVPC)和时间-强度曲线(TIC)的类型及特征。方法使用SonoLiver软件分析前列腺结节CEUS[恶性组46例、良性组37例、前列腺上皮内瘤(PIN)组27例]以获取DVPC、TIC。结果恶性组快升快降TIC为65.2%,正负双向波和正向波DVPC为41.3%、30.4%。良性组慢升慢降TIC和负向波DVPC为45.9%、51.4%。PIN组以快升快降TIC为55.6%和正负双向波DVPC为44.4%为主。3组间TIC、DVPC的差异均有统计学意义(P<0.05)。内腺结节DVPC的差异有统计学意义(P<0.05),TIC则无统计学意义(P>0.05)。外腺恶性和良性组TIC及DVPC均有统计学意义(P<0.05)。结论联合应用DVPC、TIC对前列腺结节的鉴别诊断具有一定临床价值。
Objective To analyze the types and characteristics of dynamic vascular pattern curve (DVPC) and time-intensity curve (TIC) of ultrasonographic prostatectomy (CEUS). Methods SonoLiver software was used to analyze the prostatic nodules CEUS [46 in malignant group, 37 in benign group, and 27 in prostatic intraepithelial neoplasia (PIN) group] for DVPC and TIC. Results The rate of fast rising and falling TIC in malignant group was 65.2%, and the positive and negative bidirectional wave and positive wave DVPC were 41.3% and 30.4% respectively. In benign group, slow down slow down TIC and negative wave DVPC were 45.9%, 51.4%. PIN group fast-rising fast drop TIC was 55.6% and positive and negative bidirectional wave DVPC was 44.4%. The differences of TIC and DVPC between the three groups were statistically significant (P <0.05). There was significant difference in DVPC between internal gland nodules (P <0.05) and TIC was not statistically significant (P> 0.05). TIC and DVPC in malignant and benign group were statistically significant (P <0.05). Conclusion Combined application of DVPC and TIC has certain clinical value in the differential diagnosis of prostatic nodules.