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壬苯醇醚-9和双醋氯苯胍亭对精液中和宫颈粘液中精子活动力作用的比较。这两种化合物在精液中杀精作用相同,用0.5mg/ml的药物在3分钟内就可使精子丧失活动力。当这两种化合物扩散于宫颈粘液中时,粘液中存活精子状况是有差异的。在用0.1mg/ml氯苯胍亭处理后,立即发现精子穿透受到限制并丧失活动力,而用200mg/ml氯苯胍亭长期接触后的粘液中精子却正常存活。在精子穿透粘液前将两种化合物直接混合于粘液中,氯苯胍亭仍然制动精子,但壬苯醇醚-9的浓度在精液中有杀精作用而在粘液中却没有杀精作用。不过目前大多数化学性阴道避孕药是用壬苯醇醚-9。在性交前阴道表面活性避孕药作为泡沫剂,乳胶剂或宫托剂使用,杀精作用方式是引致精子体部
Comparison of Effects of Nonoxynol - 9 and Diclofenac against Sperm Motility in Sperm and Cervical Mucus. These two compounds have the same spermicidal effect in semen, with 0.5 mg / ml of drug losing sperm motility in 3 minutes. When these two compounds diffuse in cervical mucus, the condition of surviving sperm in the mucus is different. Sperm penetration was limited and deprived of motility immediately after treatment with chlordiazepoxide at 0.1 mg / ml, whereas spermatozoa survived in mucus after long-term exposure with 200 mg / ml chlordiazepoxide kiosk. The two compounds were mixed directly into the mucus before the sperm penetrated the mucus, and the chlordiazepam kinetically arrested the sperm, but the concentration of nonoxynol-9 had spermicidal effects in the semen and no spermicidal effect in the mucus . However, at present, most of the chemical vaginal contraceptives are nonoxynol-9. Before sexual intercourse vaginal surfactant contraceptives as a foam, latex or the use of the Palace agent, spermicidal effect is caused by sperm body