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为观察地高辛对窦房结功能的影响,本文对26例窦性心动过缓者,用经食道心房调搏法,观察用地高辛前后窦房结功能,同时做血浆地高辛浓度测定,探讨该药对窦房结功能的影响。资料及方法:(一)病例选择:26例窦性心动过缓者,12例诊断病窦(简称SSS),窦房结功能均异常,14例疑似病窦,窦房结功能正常。受试者前一周停用各种影响窦房结功能药物。26例分二组:Ⅰ组(SSS 组)12例,男8例,女4例,年龄23～57岁,心电图:心率50次/分,窦性停搏1例;Ⅱ窦缓组:14例,男9例,女5例,年龄23～60(平均39)岁,心电图:心率40～60次/分。二组患者均有明显的头昏,一例有晕厥史。
In order to observe the effect of digoxin on the function of the sinus node, 26 cases of sinus bradycardia were treated with transesophageal atrial pacing method to observe the function of the sinus node before and after digoxin, while the concentration of plasma digoxin , Explore the effect of the drug on the sinus node function. Materials and Methods: (a) Case selection: 26 cases of sinus bradycardia, 12 cases of diagnosed sick sinus (SSS), abnormal sinus node function, 14 cases of suspected sick sinus, sinus node function is normal. A week before the trial participants disable all kinds of drugs that affect the sinus node function. 26 cases were divided into two groups: group Ⅰ (SSS group) 12 cases, 8 males and 4 females, aged 23 to 57 years, electrocardiogram: heart rate 50 beats / min, sinus arrest in 1 case; Ⅱ sinus bradycardia: 14 Cases, 9 males and 5 females, aged 23 to 60 (average 39) years of age, ECG: heart rate 40 to 60 beats / min. Two groups of patients had obvious dizziness, a case of history of syncope.