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肝脏是药物代谢的重要器官,药物及其代谢产物可影响肝脏的结构和功能,造成肝脏的损害。由抗菌药物引起的药物性肝损伤排在第3位。现报道1例使用抗菌药物注射用夫西地酸钠后出现黄疸的肝损伤患者,并就其发生原因、处置及保肝药物使用的合理性进行分析、总结。提示临床应用该药物时应警惕其对肝脏的不良反应,并采取积极的应对措施,合理使用保肝药物。1典型病例黄某,男,83岁,2011-06-04在我院急诊科就
The liver is an important organ of drug metabolism, drugs and their metabolites can affect the structure and function of the liver, causing liver damage. Drug-induced liver injury caused by antibiotics came in third place. Is reported in 1 case of use of antibacterial agents sodium fusidate injection of jaundiced liver injury patients, and its causes, treatment and analysis of the rationality of the use of hepatoprotective drugs were analyzed and summarized. Prompt clinical application of the drug should be wary of its adverse reactions to the liver, and take a positive response to the rational use of hepatoprotective drugs. A typical case of Hwang, male, 83 years old, 2011-06-04 in our hospital emergency department