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本文应用我院设计的《抗菌药物利用流行病学调查软件包》统计了我院876例住院病例院内感染和抗菌药物利用情况.结果表明院内感染发生率为5.5%,以呼吸系统感染为主;留置导尿、免疫抑制剂应用、致死性原发病、化疗、放疗等均为院内感染危险因素.住院患者抗菌药物应用率为69.5%,用药情况基本合理;不良反应发生率为0.2%;不合理用药现象占6.2%;以青霉素类应用比例最大,其次为头孢菌素,此外,氨基糖甙类、大环内酯类和氟喹诺酮类应用比例也较大.
In this paper, 876 hospitalized cases of nosocomial infections and antibacterials in our hospital were surveyed by using “An Epidemiological Investigation Package of Antibiotics” in our hospital.The results showed that the incidence of nosocomial infections was 5.5%, mainly respiratory infections; Indwelling catheterization, application of immunosuppressive agents, primary fatal disease, chemotherapy and radiotherapy were the risk factors of nosocomial infection.The rate of antibacterials in hospitalized patients was 69.5%, and the medication was basically reasonable; the incidence of adverse reactions was 0.2%; Rational use of drugs accounted for 6.2%; the largest proportion of penicillin, followed by cephalosporins, in addition, aminoglycosides, macrolides and fluoroquinolones a larger proportion of applications.