论文部分内容阅读
目的:观察甲硫氨酸维B1与醒脑静联合纳洛酮治疗急性重度酒精中毒的临床救治效果。方法:选取2014年01月至2015年01月收治的重度酒精中毒54例患者,随机分为三组,Ⅰ组甲硫氨酸维B1与醒脑静联合纳洛酮进行治疗,Ⅱ组患者采用醒脑静与纳洛酮进行治疗,Ⅲ组单用纳洛酮治疗,观察三组患者治疗的显效时间及症状消失时间,同时观察不良反应及并发症。结果:显效时间和症状消失时间比较,N1与N2比较差异有统计学意义(P<0.05),N1、N2与N3比较差异有统计学意义(P<0.05)。结论:甲硫氨酸维B1、醒脑静与纳洛酮联合治疗的显效时间和清醒时间优于醒脑静联合纳洛酮以及单用纳洛酮,有比较理想的临床效果。
Objective: To observe the clinical effect of methionine B1 and xingnaojing combined with naloxone in the treatment of acute severe alcoholism. Methods: Fifty-four patients with severe alcoholism who were admitted from January 2014 to January 2015 were randomly divided into three groups. GroupⅠ was treated with methionine B1 and xingnaojing combined with naloxone. Patients in group Ⅱ Xingnaojing and naloxone for treatment, Ⅲ group alone with naloxone treatment, observation of three groups of patients markedly effective treatment time and disappearance of symptoms, while observing adverse reactions and complications. Results: There was significant difference between N1 and N2 (P <0.05). There was significant difference between N1 and N2 with N3 (P <0.05). CONCLUSION: The combination of methionine B1, xingnaojing and naloxone is superior to xingnaojing combined with naloxone alone and naloxone alone in the time of onset and awake time, and has an ideal clinical effect.