龈沟液(GCF)中前列腺素E_2(PGE_2)水平与牙周病的关系正日益受到学者们的关注。本实验用放射免疫法检测牙周健康者牙齿和各种牙周病患牙的GCF—PGE_2水平,以探讨GCF—PGE_2在牙周病发病机制中的作用和将其用于临床诊断的可能性。1 资料与方法 (1)测定对象:为慢性单纯性牙龈炎患牙21例,牙周炎患牙48例,牙周组织健康牙26例。所有实验对象均测量牙龈指数(GI)、探诊深度(PD)并拍摄X线标准牙片。(2)方法:用滤纸片收集GCF,放射免疫法测定PGE_2。 表1 各组取样牙的临床指标和GCF—PGE_2水平(pg/ Gingival crevicular fluid (GCF) in prostaglandin E_2 (PGE_2) levels and periodontal disease is increasingly concerned by scholars. In this study, the level of GCF-PGE 2 in periodontal healthy teeth and various periodontal disease teeth was detected by radioimmunoassay to explore the role of GCF-PGE 2 in the pathogenesis of periodontal disease and its potential for clinical diagnosis . 1 Materials and Methods (1) Determination of objects: chronic simple gingivitis in 21 cases of teeth, 48 cases of periodontitis teeth, periodontal tissue healthy teeth in 26 cases. All subjects measured the gingival index (GI), probing depth (PD) and taken X-ray standard teeth. (2) Methods: GCF was collected with filter paper and PGE_2 was determined by radioimmunoassay. Table 1 The clinical indicators of each sample tooth and GCF-PGE 2 levels (pg /