目的：探讨槲皮素对细胞免疫功能的影响。方法：①昆明种小鼠随机分为三组：对照组、低剂量组、高剂量组。对照组每日腹腔注射生理盐水１０ｍｌ／ｋｇ，低剂量组和高剂量组每日分别腹腔注射槲皮素５０ｍｇ／ｋｇ体重和槲皮素１００ｍｇ／ｋｇ体重，连续给药５天后，用红细胞粘附花环实验测定了红细胞Ｃ３ｂ受体，用３ＨＴｄＲ释放实验和３ＨＴｄＲ掺入实验分别测定了自然杀伤（ＮＫ）细胞的杀伤效应和脾淋巴细胞增殖；②为测定白细胞介素２活性，用Ｗｉｓｔａｒ大鼠相应分组与用药后，以３ＨＴｄＲ掺入实验测定了ＣｏｎＡ诱导的ＩＬ２活性。结果：与对照组比较，实验组的ＮＫ细胞杀伤效应、脾淋巴细胞增殖及红细胞Ｃ３ｂ受体活性显著增强。此外，槲皮素能提高白细胞介素２活性并能明显对抗强的松龙所致的免疫抑制作用。结论：槲皮素有增强细胞免疫功能的作用 Objective: To investigate the effect of quercetin on cellular immune function. Methods: ① Kunming mice were randomly divided into three groups: control group, low dose group and high dose group. The control group was intraperitoneally injected with normal saline 10ml / kg, the low dose group and the high dose group were given intraperitoneal injection of quercetin 50mg / kg body weight and quercetin 100mg / kg body weight daily for 5 days, Rosette C3b receptor determination of erythrocytes, 3H  TdR release 3HTdR and 3H  TdR incorporation assay were determined by natural killer (NK) cell killing effect and spleen lymphocyte proliferation; ② To determine the activity of interleukin 2 After Wistar rats were grouped and treated with 3H-TdR incorporation assay to determine ConA-induced IL 2 activity. Results: Compared with control group, NK cell killing effect, splenic lymphocyte proliferation and erythrocyte C3b receptor activity of experimental group were significantly increased. In addition, quercetin increases interleukin-2 activity and significantly antagonizes the immunosuppressive effects of prednisolone. Conclusion: Quercetin can enhance cellular immune function