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作者对三个生产聚氯乙烯工厂共1,177名接触氯乙烯的工人进行了流行病学调查,三厂被检人数分别为345、372、451人。受检对象为所有的氯乙烯作业者,也包括既往接触氯乙烯而现已退休或改业的工人。三厂受检工人肝大的比例分别为15%、8.8%、7.1%,脾大者相对较少,最高者为3.4%。氯乙烯作业者和既往接触氯乙烯而现已调离者之间并无差异。测定了若干肝功能,包括谷草转氨酶、谷丙转氨酶、乳酸脱氢酶、胆红质、血清蛋白,仅少数人异常;但碱性磷酸酶(ALP)、谷氨酰转肽酶(GGT)升高者明显增多。ALP高于正常上限者三组分别占16.3%、24.1%及26.9%,且和接触氯乙烯时间长短呈显著相
The authors conducted an epidemiological survey of a total of 1,177 workers exposed to vinyl chloride in three PVC factories, with 345,372,451 people being inspected in each of the three factories. The subjects tested were all vinyl chloride workers and workers who had been exposed to vinyl chloride and were now retired or restructured. Three factory workers were liver large proportion of 15%, 8.8%, 7.1%, spleen were relatively small, the highest was 3.4%. There was no difference between vinyl chloride operators and those who had been exposed to vinyl chloride in the past but had been transferred. A number of liver functions were measured, including aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, bilirubin, serum proteins, and only a few abnormalities; however, alkaline phosphatase (ALP), glutamyl transpeptidase High increased significantly. The ALP levels were higher than the upper limit of the three groups accounted for 16.3%, 24.1% and 26.9%, and the contact with vinyl chloride was significantly