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目的 分析中国地区急性心肌缺血综合征病人的临床特点和治疗现状。方法 此项研究为国际性多中心关于急性心肌缺血综合征登记试验 (OASIS)的一部分。采用加拿大心血管合作协会统一设计的病例记录表 (CRF) ,自 1999年 4月开始 ,收集因急性心肌缺血入院病人的资料 ,记录病人主要临床特征和院内事件。结果 来自中国 38家医院急性心肌缺血综合征 (包括不稳定心绞痛及非Q波心肌梗死 )病人 2 2 90例 ,平均年龄 6 2 8岁 ,男性占 6 2 3%。就诊时胸痛仍未缓解者4 8 9% ;心电图异常 89 7% ,其中 4 1 4 %为相邻导联ST压低≥ 2mm ;入院诊断不稳定心绞痛90 9% ,非Q波心肌梗死 9 0 %。住院期间溶栓 3 3% ,冠状动脉 (冠脉 )造影 34 9% ,经皮冠脉腔内成形术 (PTCA) 17 6 % ,冠脉旁路移植术 (CABG) 4 2 % ,应用硝酸酯剂 99 3% ,抗血小板治疗 94 5 %。院内发生重要并发症 15 2 % ,其中死亡 1 4 %。结论 中国地区急性心肌缺血病人以不稳定心绞痛就诊居多。住院期间PTCA治疗率相对较高 ,CABG治疗率较低。死亡主要原因为严重心律失常或猝死
Objective To analyze the clinical features and treatment status of patients with acute myocardial ischemia syndrome in China. Methods This study is part of an international, multicentre registry of acute myocardial ischemia syndrome (OASIS). The CRF was designed by the Canadian Association of Cardiovascular Cooperatives. Since April 1999, data on patients admitted to hospital for acute myocardial ischemia have been collected. The main clinical characteristics and hospital events were recorded. Results A total of 22 90 patients with acute myocardial ischemia syndrome (including unstable angina pectoris and non-Q wave myocardial infarction) from 38 hospitals in China were present, with a mean age of 628 years and 62.3% of men. 49,8% of patients had chest pain at the time of diagnosis, 89 7% of them had abnormal electrocardiogram, 41% of them were ST depression of adjacent leads ≥ 2 mm, 90 9% of patients were diagnosed as unstable angina on admission, 90% . Thrombolysis during hospitalization was 33%, coronary angiography (coronary angiography) was 34.9%, percutaneous transluminal coronary angioplasty (PTCA) 17.6%, coronary artery bypass grafting (CABG) 42% Agent 99 3%, anti-platelet therapy 94 5%. 15,2% of the hospital had an important complication, of which 14% died. Conclusions The majority of patients with acute myocardial infarction in China are treated with unstable angina. PTCA treatment during hospitalization is relatively high, CABG treatment rate is low. The main cause of death is severe arrhythmia or sudden death