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LDH_x是乳酸脱氢酶中与LDH_(1～5)不同的另一种特殊类型的同功酶。自Goldberg、Blanco和Zinkham 1963年在多种哺乳动物和鸟类睾丸组织和精子中发现了LDH_x以来,其不寻常的性质特别是与性成熟和生育过程的密切关系引起了国内外学者的极大兴趣,对其生物学、生物化学、酶学、免疫学等性质作了一系列的研究,近年来从各个角度对LDH_x的临床意义及其应用进行了广泛的调查、观察和探索。 LDH_x的生物学性质 LDH_x仅存在于发育成熟的睾丸组织和精子中,由基因C位点所表达。此基因只有在精原细胞发生周期的初级精母细胞阶段
LDH_x is another special type of isozyme of lactate dehydrogenase that differs from LDH_ (1-5). Since Goldberg, Blanco, and Zinkham discovered LDH_x in many mammalian and bird testis tissues and sperm in 1963, their unusual properties, especially their close relationship with sexual maturation and fertility, have drawn great attention from domestic and foreign scholars Interest, made a series of researches on the biology, biochemistry, enzymology, immunology and other properties. In recent years, the clinical significance of LDH_x and its application have been extensively investigated, observed and explored from all angles. The biological properties of LDH_x LDH_x only exists in mature testicular tissue and sperm, expressed by the gene C site. This gene is only in spermatogonial cycle of primary spermatocyte stage