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目的:探讨硫酸镁微量气泵吸入治疗毛细支气管炎患儿的疗效及对肺功能的影响。方法:选择2012年1月-2014年8月我院收治的毛细支气管炎患儿120例,随机分为研究组和对照组各60例。两组均给予吸氧、吸痰、镇静、止咳、抗感染和支气管扩张剂治疗,研究组再加用25%硫酸镁溶液0.1~0.2ml/(kg.次)气泵吸入治疗,比较两组临床疗效及患儿肺功能变化。结果:研究组总有效率为98.3%,显著高于对照组的88.3%(P<0.05);研究组患儿咳嗽、气促、喘息、肺部哮鸣音/啰音消失时间及住院时间显著短于对照组(P<0.05);治疗后两组患儿潮气量(VT)、达峰时间比(t PTEF/t E)和v PTEF/v E均明显升高,吸呼比(Ti/Te)明显降低(P<0.05),研究组VT、t PTEF/t E和v PTEF/v E显著高于对照组,Ti/Te显著低于对照组(P<0.05)。结论:硫酸镁微量气泵吸入治疗小儿毛细支气管炎可以改善患儿喘憋、气促、呼吸困难等症状以及肺功能,临床效果较好。
Objective: To investigate the therapeutic effect of inhalation of magnesium sulfate micropump on children with bronchiolitis and its effect on pulmonary function. Methods: A total of 120 children with bronchiolitis who were admitted to our hospital from January 2012 to August 2014 were randomly divided into study group (60 cases) and control group (60 cases). Both groups were given oxygen inhalation, suctioning, sedation, cough-stopping, anti-infective and bronchodilator treatment. The study group was treated with inhalation of 0.1 ~ 0.2ml / (kg) Efficacy and changes in children with pulmonary function. Results: The total effective rate was 98.3% in the study group, which was significantly higher than that in the control group (88.3%, P <0.05). In the study group, cough, shortness of breath, wheezing, disappearance of lung wheeze / rales and hospital stay were significant (P <0.05). After treatment, the tidal volume (VTT), peak time ratio (t PTEF / t E) and v PTEF / v E in both groups were significantly higher than those in the control group (P <0.05). The PT, t PTEF / t E and v PTEF / v E in the study group were significantly higher than those in the control group, and Ti / Te was significantly lower than that in the control group (P <0.05). Conclusion: Magnesium sulfate micro-pump inhalation treatment of children with bronchiolitis can improve children with wheezing, shortness of breath, dyspnea and other symptoms and pulmonary function, the clinical effect is better.