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目的探讨患糖尿病的中国香港地区阻塞性睡眠呼吸暂停(OSA)的患病率和相关临床因素。方法入选标准为18～75岁中国香港地区2型糖尿病患者且除外不稳定临床疾病、妊娠期糖尿病或正进行肾脏替代治疗者。结果估计糖尿患者群中OSA的患病率是17.5%(男性24.7%,女性10.3%);睡眠呼吸暂停低通气指数(AHI)与BMI,老年,男性和舒张压独立相关;中重度OSA中需要≥3种抗高血压药物的校正优势比为2.48;血糖控制(HbA1c)和睡眠之间无明确关系。结论 OSA在患糖尿病的中国香港地区人群中有较高的患病率。
Objective To investigate the prevalence and related clinical factors of obstructive sleep apnea (OSA) in Hong Kong, China with diabetes mellitus. Methods The inclusion criteria were type 2 diabetic patients aged 18-75 years in Hong Kong, China with the exception of unstable clinical disease, gestational diabetes mellitus or patients undergoing renal replacement therapy. Results The prevalence of OSA in the diabetics population was estimated to be 17.5% (24.7% for males and 10.3% for females); sleep apnea-hypopnea index (AHI) was independently associated with BMI, age, male and diastolic blood pressure; moderate to severe OSA was required The adjusted odds ratio for ≥3 antihypertensives was 2.48; there was no clear relationship between glycemic control (HbA1c) and sleep. Conclusion OSA has a higher prevalence in people with diabetes mellitus in Hong Kong, China.