市场上消失了数十年的药物酞胺哌啶酮正在开始作为一种对恶性血液病患者真正有益处的药物出现。美国的报告说,89例患有非常难治的多发性骨髓瘤的病人中34％的病人用酞胺哌啶酮治疗后异常蛋白浓度减少20％。副作用包括嗜睡、意识模糊、体重减轻、恶心与呕吐。虽然早期数据表明,它可能通过抑制血管生成或干扰细胞因子(细胞素)通道发挥作用, Drug Thalidomide, a drug that has disappeared for decades in the market, is starting to emerge as a real drug of benefit to patients with hematologic malignancies. In the United States, 34% of 89 patients with very refractory multiple myeloma reported a 20% reduction in their abnormal protein concentration after treatment with thalidomide. Side effects include lethargy, confusion, weight loss, nausea and vomiting. Although early data suggest that it may play a role by inhibiting angiogenesis or interfering with cytokine (cytokine) channels,