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目的讨论未经治疗妊娠合并甲状腺功能减退(甲减)患者与甲减经治疗患者及正常孕妇在妊娠期糖尿病、胎儿生长受限、早产、羊水浑浊、产后出血等方面的影响。方法 152例分娩孕妇,其中甲减未经治疗40例作为观察组,甲减接受治疗32例作为治疗组及正常孕妇80例作为对照组,比较各组孕妇妊娠分娩结局。结果观察组羊水浑浊、胎儿生长受限、产后出血及妊娠期糖尿病发生率均高于治疗组及对照组,差异均有统计学意义(P<0.05),观察组与治疗组早产发生率比较,差异无统计学意义(P>0.05)。治疗组与对照组羊水浑浊、早产、产后出血及妊娠期糖尿病发生率比较,差异均无统计学意义(P>0.05)。结论妊娠合并甲减经治疗可降低妊娠期糖尿病、羊水浑浊、产后出血等发生率,能改善妊娠结局。
Objective To discuss the influence of untreated pregnancy with hypothyroidism (Hypothyroidism) and hypothyroidism (Hypothyroidism) and normal pregnant women on gestational diabetes mellitus, fetal growth restriction, premature delivery, amniotic fluid opacity and postpartum hemorrhage. Methods Fifty-two pregnant women of delivery were randomly divided into observation group (40 cases without hypothyroidism), hypothyroidism (32 cases) and control group (80 cases) as control group. Pregnancy and delivery outcomes were compared between groups. Results The incidence of amniotic fluid opacity, fetal growth restriction, postpartum hemorrhage and gestational diabetes mellitus in observation group were higher than those in treatment group and control group (P <0.05). The incidence of preterm birth in observation group and treatment group was significantly higher than that in treatment group The difference was not statistically significant (P> 0.05). There was no significant difference in the incidence of amniotic fluid opacity, preterm birth, postpartum hemorrhage and gestational diabetes between the treatment group and the control group (P> 0.05). Conclusion Pregnancy combined with hypothyroidism can reduce the incidence of gestational diabetes mellitus, amniotic fluid turbidity, postpartum hemorrhage and so on, can improve the pregnancy outcome.