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1969~70年,在越南的一个医院里有901例恶性疟患者,经服硫酸奎宁肠衣片、乙胺嘧啶、二氨二苯砜或磺胺异恶唑治疗后,有106例(11.8%)复发。这些复发病人在医院里再用上述药物治疗,在3个月内仍有88例继续复发。本文作者对这些复发病人的治疗方法进行了研究。在88例中,42例同时给服硫酸奎宁肠衣片每天3次,每次650毫克,连服10天,总量奎宁基质16.2克;乙胺嘧啶每天2次,每次25毫克,连服3天,总量150毫克;磺胺异恶唑每天4次,每次500毫克,连续
From 1969 to 1970, there were 901 cases of falciparum malaria in a hospital in Vietnam. After treatment with quinine sulfate tablets, pyrimethamine, diphenhydramine or sulfisoxazole, 106 (11.8%) patients relapse. The recurrence of these patients in the hospital and then treated with the above drugs, in 3 months still 88 cases continue to relapse. The authors studied the treatment of these recurrent patients. In 88 cases, 42 cases of simultaneous administration of quinine sulfate tablets 3 times a day, each 650 mg, and even for 10 days, the total amount of quinine matrix 16.2 grams; pyrimethamine 2 times a day, each 25 mg, and even For 3 days, a total of 150 mg; Sulfisoxazole 4 times a day, each 500 mg, continuous