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用Ｃ５７ＢＬ／６小鼠进行的体外实验中，在１２．５～２００Ｕ／ｍｌ剂量范围内，腹腔巨噬细胞的杀伤作用有所提高，并呈剂量依赖关系。整体实验中，将正常鼠及荷瘤鼠分别注射ｒｈＩＬ－６和生理盐水，连续１０ｄ，第１５天杀鼠取腹腔巨噬细胞观察其杀伤能力，结果发现，不论在荷瘤或未荷瘤鼠中，ｒｈＩＬ－６均可提高腹腔巨噬细胞的杀瘤功能；与对照组相比，杀伤率平均增加２１．３１％和３８．６０％，与此同时腹腔巨噬细胞总量亦有所增加。
In in vitro experiments with C57BL/6 mice, the killing effect of peritoneal macrophages increased in a dose range of 12.5 to 200 U/ml in a dose-dependent manner. In the whole experiment, normal and tumor-bearing mice were injected with rhIL-6 and normal saline respectively for 10 days. The killing ability of peritoneal macrophages on the fifteenth day was observed. The results showed that both the tumor-bearing and non-tumor-bearing mice In addition, rhIL-6 increased tumoricidal function of peritoneal macrophages. Compared with the control group, the killing rate increased by an average of 21.31% and 38.60%. At the same time, the total number of peritoneal macrophages increased. .