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目的：观察伊拉地平对１１例轻、中度高血压及其中６例合并肾功能损害者的疗效。方法：高血压病人１１例（男性７例，女性４例；年龄５４±ｓ１３ａ）采用伊拉地平缓释胶囊５～１０ｍｇ／ｄ单一口服，疗程１～３ｍｏ。结果：收缩压平均降低２．４±０．５ｋＰａ，舒张压平均降低２．５±０．４ｋＰａ，１１例中随机取７例作了有效肾血浆流量（ＥＲＰＦ）肾小球滤过率（ＧＦＲ）检查，其中ＥＲＰＦ明显增加，平均增加１６０±６６ｍＬ／ｍｉｎ，滤过分数（ＦＦ）降低４％，并且有排钠、利尿效应。结论：伊拉地平除有降压效应外，且有保护肾功能的作用。
Objective: To observe the efficacy of idladapine in 11 patients with mild to moderate hypertension and 6 patients with renal dysfunction. Methods: Eleven patients with hypertension (7 males and 4 females; age 54 ± s13a) were treated with a single oral dose of 5 ~ 10 mg / day of ilapirtin sustained release capsules for 1 ~ 3 months. Results: Systolic blood pressure decreased by 2.4 ± 0.5kPa on average and diastolic blood pressure decreased by 2.5 ± 0.4kPa. Seven of 11 patients were randomly selected to receive effective renal plasma flow (ERPF) glomerular filtration rate (GFR ) Examination, in which ERPF significantly increased, with an average increase of 160 ± 66mL / min, filtration fraction (FF) decreased by 4%, and sodium, diuretic effect. Conclusion: In addition to its antihypertensive effect, it also has the function of protecting renal function.