论文部分内容阅读
甘胆酸(简称CG)是主要胆酸之一,是肝脏以胆固醇为原料合成的胆酸再与甘氨酸结合而成。它在人血清中主要以蛋白结合形式存在。甘胆酸正常代谢为甘胆酸肠肝循环。肝内合成、由胆囊贮存,在肠内被吸收,经门静脉极大部分被肝摄取,被溢流进入体循环总量小于1％。肝细胞受损或肝有疾病、胆汁淤滞时,就引起甘胆酸代谢和循环紊乱,血中甘胆酸增加。根据这一现象,我院于1986年起,对94例轻、重肝脏病人、48例正常人和27例非肝疾患者进行甘胆酸放射免疫测定,现将测定结果以及临床意义分析如下: 一、方法:采用FJ—2003/018、~(125)I免疫测量仪和北京原子能研究院出产的甘胆酸放射免疫分析药盒测试而成。具体步骤:略。
Glycocholic acid (referred to as CG) is one of the main bile acids, is the liver of cholesterol as raw material for the synthesis of bile acid and then combined with glycine. It exists predominantly in human serum as a protein-bound form. The normal metabolism of glycocholate is glycocholate enterohepatic circulation. Intrahepatic synthesis, stored by the gallbladder, is absorbed in the intestine, and most of the portal vein is taken up by the liver and overflowed into the systemic circulation in less than 1% of the total volume. Hepatic cell damage or liver disease, cholestasis, it caused by glycocholic acid metabolism and circulatory disorders, increased blood glycocholate. According to this phenomenon, our hospital since 1986, 94 cases of light and heavy liver patients, 48 normal subjects and 27 cases of non-liver disease patients with glycocholic acid radioimmunoassay, the measurement results and clinical significance are as follows: First, the method: FJ-2003/018, ~ (125) I immunoassay and Beijing Institute of Atomic Energy produced by the glycocholate radioimmunoassay kit test. Specific steps: slightly.