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目的:~(18)F-FDG PET/CT在肺部病变定性中的灵敏度很高,但仍有时出现漏诊。本文通过分析12例~(18)F-FDG PET/CT漏诊病例,探究其特点及原因,探索提高~(18)F-FDG PET/CT诊断肺部病变灵敏度的方法。方法:收集2014年5月到2016年1月~(18)F-FDG PET/CT检查结果为阴性但术后病理结果为恶性病变的12例肺部病变病例。采用SPSS18.0软件对结果进行分析。结果:漏诊12例中鳞癌1例,腺癌10例,转移癌1例,平均直径为3.33±2.38cm,平均SUV(MAX)为8.32±4.71,其中5例的直径小于1cm。结论:假阴性病例中腺癌比例最高。肿块直径越小,越容易漏诊,尤其是直径小于1cm的恶性肿瘤。注意对SUV(max)的客观评价,综合病变大小和临床病史以及实验室检查结果进行诊断,才能提高PET/CT诊断的灵敏度,减少漏诊。
PURPOSE: ~ (18) F-FDG PET / CT is highly sensitive in the characterization of lung lesions but missed diagnosis is sometimes found. In this paper, we analyzed the characteristics of missed cases of ~ 18 F-FDG PET / CT and explored the methods to improve the sensitivity of ~ (18) F-FDG PET / CT in the diagnosis of pulmonary lesions. Methods: From May 2014 to January 2016, a total of 12 cases of pulmonary lesions were collected. The results of F-FDG PET / CT were negative but the pathological results were malignant. The results were analyzed by SPSS18.0 software. Results: Misdiagnosis of squamous cell carcinoma in 12 cases, adenocarcinoma in 10 cases, metastatic carcinoma in 1 case, the average diameter of 3.33 ± 2.38cm, the average SUV (MAX) was 8.32 ± 4.71, of which 5 cases were less than 1cm in diameter. Conclusion: The highest proportion of adenocarcinomas in false-negative cases. The smaller the diameter of the tumor, the easier it is to misdiagnose, especially malignant tumors less than 1 cm in diameter. Attention to objective evaluation of SUV (max), combined with the size of the lesion and clinical history and laboratory test results in order to improve the sensitivity of PET / CT diagnosis and reduce missed diagnosis.