论文部分内容阅读
目的利用超声检测中孕期胎儿鼻骨发育,探讨超声测量胎儿鼻骨在检出染色体异常疾病的价值及临床意义。方法 2010-01-2010-12来广西壮族自治区妇幼保健院进行中孕期常规超声检查及胎儿系统超声筛查的孕妇进行鼻骨检测,对超声检查鼻骨异常者行染色体核型分析。结果 71 984例常规产前超声检查及产前超声系统筛查的孕妇,发现鼻骨缺失或发育不良者84例,合并有其他结构畸形22例,其中有染色体异常者32例(21-三体24例,18-三体7例,13-三体1例)。结论中孕期超声检测胎儿鼻骨对发现染色体异常有一定的临床实用价值,不失为一种简便、安全、可重复、非侵入性、孕妇易于接受的产前检查方法。
Objective To detect the development of fetal nasal bone in the second trimester by ultrasound and explore the value and clinical significance of fetal nasal bone in the detection of chromosomal abnormalities by ultrasound. Methods 2010-01-2010-12 Guangxi Zhuang Autonomous Region Maternity and Child Care Hospital for pregnant women during routine ultrasound examination and fetal ultrasound screening of pregnant women for nasal examination, ultrasound examination of nasal bone abnormalities line karyotype analysis. Results 71 984 routine prenatal ultrasound and prenatal ultrasound screening of pregnant women found that 84 cases of nasal bone loss or hypoplasia, combined with other structural abnormalities in 22 cases, of which 32 cases of chromosomal abnormalities (21 trisomy 24 Cases, 18-trisomy in 7 cases, 13-trisomy in 1 case). Conclusion It is a simple, safe, repeatable, noninvasive and easily accepted prenatal method to detect fetal nasal bone during pregnancy.