【摘 要】
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Fourteen new di n butyltin(IV) complexes of hydroxamic acids of the formula Bu 2 SnL 2 (HL=hydroxamic acids) were synthesized by the reaction
【出 处】
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Chinese Journal of Chemistry
论文部分内容阅读
Fourteen new di n butyltin(IV) complexes of hydroxamic acids of the formula Bu 2 SnL 2 (HL=hydroxamic acids) were synthesized by the reaction of Bu 2 SnO and hydroxamic acids in dry toluene and ethanol media. The compounds were characterized by elemental analyses, molecular weight, IR and 1 H NMR spectroscopy. The results indicate that n Bu 2 SnL 2 have distorted trans octahedral structure. The antitumor activity in vitro against human A 549 tumor cells and P388 leukemia was presented, and their structure activity relationship was discussed.
Fourteen new di n butyltin (IV) complexes of hydroxamic acids of the formula Bu 2 SnL 2 (HL = hydroxamic acids) were synthesized by the reaction of Bu 2 SnO and hydroxamic acids in dry toluene and ethanol media. The compounds were characterized by elemental analysis of molecular weight, IR and 1 H NMR spectroscopy. The results indicate that Bu 2 SnL 2 has a distorted trans octahedral structure. The antitumor activity in vitro against human A 549 tumor cells and P388 leukemia was presented, and their structure activity relationship was discussed.
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