A novel framework for non-Manhattan channel routing considering crosstalk and wire length reduction is proposed. To handle crosstalk and wire length reduction problem, an improved non-Manhattan router in the gridded routing model is developed, and a novel rerouting algorithm based on segment-rerouting technique and layer reassignment is presented. Simulation experiments demonstrate that our algorithm achieves very good results. A novel framework for non-Manhattan channel routing considering crosstalk and wire length reduction is proposed. To handle crosstalk and wire length reduction problem, an improved non-Manhattan router in the gridded routing model is developed, and a novel rerouting algorithm based on segment- Simulation experiments demonstrate that our algorithm achieves very good results.