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再灌注是治疗缺血性心脏病的常用措施,但再灌注常导致心律失常、心肌舒缩功能障碍及心肌细胞不可逆损伤加重等并发症的发生,引起心肌缺血再灌注损伤(MIRI)。本文从MIRI的治疗原则和相关药物研究进行综述。
Reperfusion is a commonly used measure to treat ischemic heart disease. However, reperfusion often leads to the occurrence of complications such as arrhythmia, cardiac systolic and diastolic dysfunction, and irreversible injury of myocardial cells, resulting in myocardial ischemia-reperfusion injury (MIRI). This article reviews the principles of MIRI treatment and related drug research.