新生儿高胆红质血症是产科及儿科医师最常遇到的问题之一。胎儿的胆红质依靠胎盘及母体进行分解及排泄。分娩后,新生儿尚不能独立进行如此代谢活动,主要有以下数项影响其代谢。1. 因其红细胞寿命短,致使有较多的红细胞分解产物需至肝脏结合。2. 新生儿网状内皮系统功能低下。3. “Y”蛋白溶度减低,而“Y”蛋白为胆红质分子的主要结合蛋白。 Hypercholesterolemia in neonates is one of the most common problems encountered by obstetric and pediatricians. Fetal bilirubin rely on the placenta and maternal decomposition and excretion. After delivery, the newborn can not independently carry out such metabolic activity, mainly the following several affect their metabolism. 1. Because of its short life expectancy of red blood cells, resulting in more red blood cell decomposition products to the liver. Neonatal reticuloendothelial system dysfunction. 3. The “Y” protein is reduced in solubility, while the “Y” protein is the major binding protein for the bilirubin molecule.