结直肠癌根治术后单纯性肺转移60例临床病例分析

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目的:结直肠癌患者根治术后大约有50%会发生远处转移,最常见的转移部位是肝,其次是肺,本文旨在探讨结直肠癌根治术后肺转移的特点、治疗效果和影响预后的因素。方法:随访1967年至2002年间的结直肠癌根治术后发生单纯性肺转移的60例病例,对其临床资料进行回顾性分析和总结。结果:自原发灶切除术后全组病例中位生存时间37个月,其中有15例行转移灶的切除手术,中位生存51个月;其余45例行非手术治疗,中位生存34个月;转移瘤大于3个组生中位生存时间30月,转移瘤小于等于3个组中位生存时间43个月。患者的总生存率可能和是否手术、转移灶的个数有关,而年龄、性别、原发灶病理类型、分期、转移灶大小对生存率无明显影响。结论:结直肠癌根治术后单纯性肺转移的积极治疗是有效的,手术及转移灶个数可能是影响治疗效果的因素。 Objective: Colorectal cancer patients after radical surgery about 50% distant metastasis, the most common metastatic site is the liver, followed by the lung, this paper aims to investigate the characteristics of colorectal cancer after lung metastases, the treatment effect and impact Prognostic factors. Methods: Sixty cases of simple lung metastasis after radical operation of colorectal cancer from 1967 to 2002 were followed up. The clinical data were retrospectively analyzed and summarized. Results: The median survival time was 37 months after the resection of the primary tumor. Among them, 15 cases underwent resection of the metastases with a median survival of 51 months. The remaining 45 cases underwent non-surgical treatment and the median survival was 34 Months; the median survival time of metastasis> 3 groups was 30 months, and the metastasis was less than or equal to 3 groups. The median survival time was 43 months. The overall survival rate of patients may be related to the number of surgical operations and metastases. However, age, gender, pathological type of primary tumor, staging, and size of metastases have no significant effect on the survival rate. Conclusion: The active treatment of simple lung metastasis after radical operation of colorectal cancer is effective. The number of operation and metastasis may be the factors affecting the therapeutic effect.
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