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近年来,有关解脲脲原体(UU)感染与盆腔炎症性疾病(PID)的关系报道较多。但生殖道UU感染与输卵管妊娠的关系研究报道甚少。为此,我们应用更为灵敏、特异的套式(Nested)PCR技术检测了17例输卵管妊娠患者的宫颈拭子UU-DNA,并以同期536例非输卵管妊娠妇科住院病人宫颈拭子为对照组。检测结果为,前者阳性率为76.5%,而后者仅为21.4%,有显著性差异(P<0.05)。作者认为UU感染所致的输卵管急慢性炎症是输卵管妊娠的重要原因。作者建议:婚龄妇女应定期作UU生殖道感染检查,阳性者及时治疗,以防止PID和输卵管妊娠的发生。
In recent years, the relationship between UU infection and pelvic inflammatory disease (PID) has been reported more. However, there are few reports on the relationship between genital UU infection and tubal pregnancy. To this end, we applied a more sensitive and specific nested PCR technique to detect UU-DNA of 17 cases of tubal pregnancy patients with cervical swabs, and compared with 536 cases of non-tubal gynecological inpatients with cervical swab in the same period as the control group . The test results showed that the former positive rate was 76.5%, while the latter was only 21.4%, there was a significant difference (P <0.05). The authors believe that UU infection caused by tubal acute and chronic inflammation is an important cause of tubal pregnancy. The authors suggest: women of childbearing age should be regularly UU genital tract infection checks, positive prompt treatment to prevent the occurrence of PID and tubal pregnancy.