赵来越多的患者因为血清总ＰＳＡ的升高而行前列腺活检 ,但总ＰＳＡ缺乏足够的特异性。ＰＳＡ以游离形式及几种结合形式存在 ,已有报告称游离 /总ＰＳＡ比值可以提高ＰＳＡ处于灰区的前列腺癌的诊断率 ,也有研究认为患前列腺癌时变化更多的是结合ＰＳＡ。本研究对Ｂａｙｅｒ公 Zhao more patients because of the serum total PSA prostate biopsy, but the total lack of specificity of the PSA. PSA exists in free form and in several forms of conjugation. It has been reported that the free / total PSA ratio can improve the diagnostic rate of prostate cancer in the gray zone of PSA. Some studies suggest that PSA changes more frequently in patients with prostate cancer. This study is of Bayer public