金黄色葡萄球菌一方面具有形成脓肿,另一方面有通过菌血症而形成转移性病灶的特性。对于最近引人注目的新青霉素耐药性金黄色葡萄球菌(MRSA),并没有发现它的病原性比新青霉素敏感性菌(MSSA)低的证据。MRSA不仅易引起患有基础疾病的患者感染,而且因其对大多数常用抗菌素具有耐药性,所以其感染病例多难以治疗。本文仅就MRSA败血症的临床,以对难治性血液疾病患者的诊治为中心加以概述。一、背景因素与主要由中性粒细胞担负杀菌作用的绿脓菌相比,担负杀灭金葡菌的主要是巨噬细胞,然而MRSA是在伴有急性白血病患者等的中性粒细胞减少的败血 Staphylococcus aureus, on the one hand, has the ability to form abscesses and, on the other hand, to develop metastatic lesions through bacteremia. No evidence of its lower pathogenicity than new penicillin-susceptible bacteria (MSSA) has been found for the recent eye-catching new penicillin-resistant Staphylococcus aureus (MRSA). Not only is MRSA susceptible to infection in patients with underlying diseases, but it is also more difficult to treat because of its resistance to most commonly used antibiotics. This article only on the clinical MRSA sepsis, to diagnosis and treatment of patients with refractory hematological disease as the center to be outlined. First, the background factors and mainly by the neutrophil bacteriostasis Pseudomonas aeruginosa bacteria responsible for killing Staphylococcus aureus is mainly macrophages, however, MRSA is associated with acute leukemia patients and other neutropenia The septicemia