对８６例恶性血液病患者进行随机分组，甲组４２例，乙组４４例，采用双盲法于化疗前予不同剂量枢复宁防治恶心呕吐。结果两组对呕吐的完全控制和基本控制率分别为甲组９０．５％，乙组８８．７％（Ｐ＞０．０５）。对化疗后２４小时内恶心的控制两组亦无显著差异。提示枢复宁单剂量静注可取得较好止吐效果。 Eighty-six patients with hematologic malignancies were randomly divided into two groups: 42 cases in group A and 44 cases in group B. Double-blind method was used to prevent and treat vomiting and nausea and vomiting by different doses of xiao-fu-ning before chemotherapy. Results The complete control and basic control rate of vomiting in both groups were 90.5% in group A and 88.7% in group B (P> 0.05). Nausea control within 24 hours after chemotherapy was no significant difference between the two groups. Tip Shu-Ning Ning single dose intravenous injection can achieve better antiemetic effect.