本文分别检测了57名正常人和205名接触二基甲酰胺工人尿中甲基甲酰胺含量及空气中二甲基甲酰胺浓度．正常组空气二甲基甲酰胺浓度低于0．25mg／m3．尿中甲基甲酰胺末检出，接触组空气中二甲基甲酰胺平均浓度变为7．68±3．05mg／m3，工人班末尿中甲基甲酰胺平均含量为4．40±3．25mg／g肌酐．结果表明，班末尿中甲基甲酰胺含量及检出率与空气中二甲基甲酰胺浓度显著相关．班末尿中甲基甲酰胺含量能更客观地反映工人二甲基甲酰胺接触程度．因此它可作为甲基甲酰胺接触者一项有价值的生物监测指标． In this paper, we examined the urinary methylformamide content and the dimethylformamide concentration in air of 57 normal persons and 205 workers exposed to di-formamide respectively. Normal group air dimethylformamide concentrations below 0.25mg / m3. The urinary methylformamide was detected, the average concentration of dimethyl formamide in the air of the exposure group was 7.68 ± 3.05mg / m3, and the average content of methyl formamide in the urine of workers was 4.40 ± 3 .25mg / g creatinine. The result showed that the content of methylformamide and the detection rate of the urine in the shift were significantly correlated with the concentration of dimethylformamide in the air. Methylformamide in the urine at the end of the shift can more objectively reflect the degree of exposure of workers to dimethylformamide. It therefore serves as a valuable biological monitoring indicator of methylformamide exposure.