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目的探析小儿胃炎应用奥美拉唑与克拉霉素治疗效果对比。方法 86例胃炎患儿,根据用药不同分为研究组(45例)和参照组(41例)。参照组给予奥美拉唑,研究组给予奥美拉唑联合克拉霉素,分析比较两组的临床效果。结果研究组总有效率为95.6%(43/45),显著高于参照组的78.0%(32/41),差异具有统计学意义(χ2=5.89,P<0.05);研究组患儿不良反应的发生率为6.7%(3/45),显著低于参照组的26.8%(11/41),差异具有统计学意义(χ2=6.40,P<0.05)。结论小儿胃炎应用联合奥美拉唑克拉霉素的临床效果显著,可以有效提高患儿的治愈率,缩短治疗时间,降低不良反应的发生率,临床应用价值高。
Objective To compare the therapeutic effects of omeprazole and clarithromycin in children with gastritis. Methods Eighty - six children with gastritis were divided into study group (45 cases) and reference group (41 cases) according to different medication. The reference group was given omeprazole, and the study group was given omeprazole combined with clarithromycin. The clinical effects of the two groups were analyzed and compared. Results The total effective rate was 95.6% (43/45) in the study group, which was significantly higher than that in the reference group (78.0%, 32/41) (χ2 = 5.89, P <0.05) The incidence was 6.7% (3/45), which was significantly lower than that of the reference group (26.8%, 11/41). The difference was statistically significant (χ2 = 6.40, P <0.05). Conclusion The clinical effect of combination of omeprazole and clarithromycin in children with gastritis is significant, which can effectively improve the cure rate, shorten the treatment time and reduce the incidence of adverse reactions in children with high clinical value.